I am based in Cali, Colombia, and employed part time by CIDEIM and part time by LSHTM. I work largely on dengue, leishmaniasis, lymphatic filariasis and other parasitic and vector-borne diseases.
I previously worked at the Papua New Guinea Institute of Medical Research, and the Ahmadu Bello University in Kaduna, Nigeria (seconded from the Institute of Ophthalmology, London).
In 1998 I completed a PhD supervised by Bryan Grenfell in the Department of Zoology, University of Cambridge entitled 'Heterogeneity and the Epidemiology of Lymphatic Filariasis'. I also have a BA in Mathematics and a Diploma in Mathematical Statistics from the same university.
Interested with vector Borne Disease mainly (Mosquitoes,Sand fly) and their interaction with diseases, Molecular biology and Bioinformatic.
Biting midges and black flies, specifically the ecological drivers of their avian malaria transmission ability and interactions with endosymbionts
The epidemiology, control, transmission dynamics, and mathematical modelling of neglected tropical diseases (NTDs) in general and filarial infections in particular. Currently focusing on refining transmission models of onchocerciasis control and elimination under the umbrella of the NTD Modelling Consortium. Parameterising models with field-derived data, including vector bionomics, vector-parasite-host interactions, parasitological and entomological data, and statistical analyses of datasets. Interest in blackfies and their transmission dynamics to better understand the impact of control interventions, including antivectorial and antiparasitic measures.
Infectious disease ecology and evolution; epidemiology, molecular ecology, vector biology
Working on bluetongue and Lyme disease among other (mostly non-vector-borne diseases)
My current research interests lie in investigating vector competence for arboviruses. I am particularly interested in the effect of temperature on virus transmission, including the minimum environmental temperature required for transmission, to identify regions at risk from invasive or endemic viruses. I am also interested in the potential for viruses to adapt to different conditions, and consequently, the risk they may pose in the future.
I am fascinated by the biology and ecology of the vectors - their diversity and capacity to transmit varios vector-born disease. My research is mainly focused on faunistic diversity of Culicoides biting midges and their role in the vector-parasite and vector-host interactions in the parasite-vector-host system of biting midges, avian haemosporidians and birds.
Systematics, ecology, behaviour, vectors, morphology, fossil record (everything to do with Ceratopogonidae); systematics of other families of Culicomorpha.
My PhD research involves the identification of Culiocides biting midge species currently found in Trinidad using ecozonation; as well as the determination of which serotypes of Culicoides-vectored Bluetongue (BTV) and Epizootic Haemorrhagic Disease (EHDV) viruses are circulating in Trinidad using a naïve cohort of cattle. Additional research involved the comparison of the different types of traps (incandescent light, UV light, semio-chemical baited and sweep-nets) with respect to Culicoides specimen and species yield and their crepuscular activity.
I am Honorary Assistant Professor at London School of Hygiene and Tropical Medicine and Head of Development & Partnerships at the university's first biotech spin-out Vecotech Ltd. I lead research developing novel attractant and repellent products for pest arthropods. My research interests lie with increasing the understanding the behavioural biology of pest arthropods and in developing novel surveillance and control tools targeting them.
Sampling, surveillance, and chemical ecology of vectors, particularly sandflies, for improving control and understanding the transmission of vector-borne diseases.
Vector Ecology - Vector Biogeographic Distribution - Health Promotion and Vector Borne Disease Prevention Programs
Morphological and molecular taxonomy of Culicoides
Host preference studies
Detection of Bluetongue and related viruses in Midges
culicoides species diversity in wild life
My work has had a broad impact on the establishment of new genomic model species to complement those (e.g., Saccharomyces, Drosophila, Caenorhabditis, Mus) that have transformed our understanding of the human condition by laboratory studies, yet now chosen because of a deeper understanding of their ecologies, and a greater ability to sample and study genetic variants within their natural populations. These include the waterfea Daphnia (Colbourne et al. 2011 Science 331: 555-561), the jewel wasp Nasonia (Werren et al. 2010 Science 327:343-348), the green anole lizard Anolis (Alföldi et al. 2011 Nature 477:587-591) and the brown planthopper Nilaparvata (Zhang et al. 2014 Genome Biology 15:521). Other vertebrates include the killifish Fundulus (Reid et al. 2017 Genome Biology and Evolution 9:659-676), the songbird Junco and a growing list of emerging invertebrate model species including bee, black fly, aphid, tick, mosquito (Tormey et al. 2015 BMC Genomics 16:754) and amphipod (Poynton et al. 2018 Environmental Science and Technology 52:6009-6022). This work resulted in Daphnia's designation as a biomedical model species by the US National Institutes of Health.
Studies that focused on these new model species are producing the broad range of anticipated discoveries that would be difficult to achieve otherwise; many are suggesting that variation among the co-regulated networks of genes are better predictors than gene variation of the adaptive potential of populations to survive environmental stress (Reid et al. 2016 Science 354:1305-1308), of the mechanisms that confer insecticide resistances in arthropods (Weston et al. 2013 PNAS 110:16532), of the mechanistic basis of environmentally induced phenotypic plastic traits (Shaw et al. 2014 Molecular Biology and Evolution 31:3002-3015), and the evolutionary basis of the vector biology of mosquitos (Bradshaw et al. 2017 PNAS 115:1009-1014).
I am broadly interested in systematics, taxonomy and natural history of lower Diptera, with expertise in Psychodomorpha (Blephariceridae, Tanyderidae and Psychodidae).
Culicoides-borne pathogens of veterinary importance; host-vector-pathogen interface; role of insect saliva on pathogen dissemination and virulence; host immune responses to insect blood-feeding and insect saliva
pathogen-host interactions (pathogenesis, immunology, vaccinology) of emerging and vector-borne diseases with attention to the role of the vector in pathogen transmission
Novel strategies for transmisssion-blocking
Leishmaniasis, Chagas, Arbovirus.
Medical Biologist and currently in 2nd year of PhD. I hold a Master degree's in Parasitology-Entomology and a Certificate of Medical Entomology from Institut Pasteur in Paris.
I am interested in vector-borne diseases and their vectors. Particularly epidemiology of leishmaniasis and sandflies bioecology in Burkina Faso.
I have interest in wildlife animal diseases. I want to know details about biting midges, their life cycle, effect on animals and remedy from them. I did work on antimicrobial resistance of Rhesus monkey. I am interest in work on controlling vector borne disease of livestock as well as wild animals. That I can take steps to conservation of last member of extinct species of wildlife. I want to build my carrier as a wildlife biologist and conservationist in future.
Epidemiology of Vector-Borne Zoonotic diseases, Vector control and management, Emerging Infectious disease.
Biology of bloodfeeding insects, vector-borne diseases, ecology of sand flies (Diptera: Phlebotominae), molecular taxonomy and phylogeny, epidemiology of Old World leishmaniases
Climate impact assessment on the global burden of vector-borne diseases. Mathematical modelling of population dynamics and disease epidemiology for various vectors and pathogens.
Mark Fife leads the Genetics and Genomics group at The Pirbright Institute. He is a complex-disease geneticist with extensive experience in complex trait analysis (QTL and association studies), candidate gene mapping and molecular biology techniques. He has produced over 45 peer-reviewed publications and book chapters in this area before becoming a group leader at the Institute. His work has been the focus of extensive genome-wide and haplotype analysis using web-based SNP selector software that he has implemented at Pirbright. This work has culminated in the identification and characterisation of several causal genes for important immune traits in chickens and potential vector competence genes in Culicoides Midges.
Dr. Fife has extensive expertise in coordinating multidisciplinary and multi-site projects. He is an active STEM (Science, Technology, Engineering and Mathematics) ambassador which creates opportunities to inspire young people and develop their creativity, problem-solving and employability skills for the UK's future competitiveness.
Research interest is on application of molecular biology tools and immunological techniques in the study of vector biology for possible control and elimination.
I am interested to work on sand fly ecology, behaviour, breeding sites and feeding preferences. Also interested to learn about gnats and black flies also.
1.Laboratory rearing techniques for insects and insect vectors.
2.Molecular characterisation of insects and insect vectors
3. Ecological and predisposing insect-vector interractions.
We have maintained the only known colony of black flies (Simulium vittatum cytospecies IS-7) for the past 27 years. A wide variety of research projects have been conducted with specimens from this colony and eggs and adults are readily available for approved collaborators. Our particular interest is Commercial Research and Development associated with the biological larvicide Bacillus thuringiensis subsp. israelensis and larval feeding, although adult feeding studies are currently being conducted. I have also worked on three continents conducting and advising black fly suppression programs. This work includes personally operating a localized black fly suppression program for the past 24 years in the southeastern United States.
spatial epidemiology, distribution modelling and mapping, risk modelling and mapping, Culicoides, animal health, One Health,arboviruses, surveillance
- Ultrastructure of Biting Midges and Sandflies
- Behavior of Biting Midges and Sandflies
- Ecology of saltmarsh breeding Biting Midges
- Insect attractants for Biting Midges
My research interests focus on combining field entomology and ecology with genetic and genomic characterisation of Culicoides to investigate vector-virus-host interactions for economically important arboviruses including bluetongue virus, African horse sickness virus, Schmallenberg virus and Oropouche orthobunyavirus. I specialise in high containment arbovirology studies and the establishment of vector surveillance networks and research projects in logistically difficult areas.
Bionomics of biting midges,bio systematics,insect microbiology,Laboratory rearing of important species of Culicoides and studying their life history traits
Working with ACDP3/SAPO4 pathogens within Biosafety Level 3 (BSL3) facilities in order to carry out vector competence studies in arthropods (mosquitoes). This also includes the preparation of SOPs and Biological Risk Assessments as well as training junior staff.
Characterization of arboviruses of medical and veterinary importance (e.g., Zika virus, West Nile virus, Rift Valley Fever virus, Usutu virus, Batai virus, Japanese Encephalitis virus) for which I have experience in tissue cell culture for virus propagation and titration, RT qPCR, DNA/RNA extraction methods and sequencing as well as serological tests.
Management of arbovirus laboratory and insectary facilities within BSL3 as well as non-containment, and line management of junior staff.
Molecular approaches and application of non-destructive techniques for vector species delineation using genetic markers such as COI DNA barcoding, ITS2, as well as for the identification of host DNA within arthropod’s blood meals (Xenosurveillance).
Application of molecular techniques for pathogens detection in arthropods such as ticks, sand flies, and mosquitoes, e.g. Piroplasms, bacteria, tick borne encephalitis.
Preparation of scientific publications, grant applications, attending national and international meetings, establishment of international collaboration, and provision of consultancy in animal health as well as communication with DEFRA stakeholders and senior management.
Curatorial experience, and collection and field-based research towards the systematics of arthropods of medical/ veterinary importance (e.g., mosquitoes, ticks, black flies, sand flies) as well as of agricultural relevance (e.g., plant bugs, termites).